M2 | Spinal Mechanisms for Sensorimotor Integration (9/14) -- KINES 531: Neural Control of Movement

M2 | Spinal Mechanisms for Sensorimotor Integration Peripheral Sensory Neuronopathy Peripheral sensory neuronopathy A person with a disease that kills proprioceptive neurons has severe problems with the simplest of movements. The average person has no difficulty raising a coffee mug: Source: Demo: proprioception makes raising a coffee mug easy (52 sec) | HHMI’s BioInteractive Charles Freed has lost proprioceptive information and, consequently, has difficulty raising a coffee mug: Source: Without proprioception, raising a mug is difficult (1 min 38 sec) | HHMI’s BioInteractive In the absence of proprioceptive feedback, some individuals can compensate by using visual feedback: Source: Ian Waterman: Compensating for proprioceptive loss (1 min 41 sec) | HHMI’s BioInteractive Proprioceptive feedback makes it easy to touch one’s thumb to one’s fingers without looking: Source: Demo: Touching thumb to fingers with proprioception (56 sec) | HHMI’s BioInteractive In the absence of proprioception and visual feedback, it is impossible to touch thumb to fingers accurately. Source: Waterman touching thumb to fingers without proprioception (1 min 15 sec) | HHMI’s BioInteractive