10.5 Fractures: Bone Repair
Learning Objectives
By the end of this section, you will be able to:
- Differentiate among the different types of fractures
- Describe the steps involved in bone repair
A fracture is a broken bone. It will heal whether or not a physician resets it in its anatomical position. If the bone is not reset correctly, the healing process will keep the bone in its deformed position.
When a broken bone is manipulated and set into its natural position without surgery, the procedure is called a closed reduction. Open reduction requires surgery to expose the fracture and reset the bone. While some fractures can be minor, others are quite severe and result in grave complications. For example, a fractured diaphysis of the femur has the potential to release fat globules into the bloodstream. These can become lodged in the capillary beds of the lungs, leading to respiratory distress and if not treated quickly, death.
Types of Fractures
Fractures are classified by their complexity, location, and other features (Figure 10.5.1). Table 10.5.1 outlines common types of fractures. Some fractures may be described using more than one term because it may have the features of more than one type (e.g., an open transverse fracture).
Table 10.5.1 Types of Fractures
| Type of fracture | Description |
| Closed (or simple) | A fracture in which the skin remains intact |
| Comminated | Several breaks result in many small pieces between two large segments |
| Greenstick | A partial fracture in which only one side of the bone is broken |
| Impact | One fragment is driven into the other, usually as a result of compression |
| Oblique | Occurs at an angle that is not 90 degrees |
| Open (or compound) | A fracture in which at least one end of the bone tears through the skin; carries high risk of infection |
| Spiral | Bone segments are pulled apart as a result of a twisting motion |
| Transverse | Occurs straight across the long axis of the bone |
Bone Repair
When a bone breaks, blood flows from any vessel torn by the fracture. These vessels could be in the periosteum, osteons, and/or medullary cavity. The blood begins to clot, and about six to eight hours after the fracture, the clotting blood has formed a fracture haematoma (Figure 10.5.2a). The disruption of blood flow to the bone results in the death of bone cells around the fracture.
Within about 48 hours after the fracture, chondrocytes from the endosteum have created an internal callus (plural = calli) by secreting a fibrocartilaginous matrix between the two ends of the broken bone, while the periosteal chondrocytes and osteoblasts create an external callus of hyaline cartilage and bone, respectively, around the outside of the break (Figure 10.5.2b). This stabilises the fracture.
Over the next several weeks, osteoclasts resorb the dead bone; osteogenic cells become active, divide, and differentiate into osteoblasts. The cartilage in the calli is replaced by trabecular bone via endochondral ossificatio