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I have 2 pythons on my mac (10.8.3): The default, and 2.7 version from homebrew.
So far, I could install modules and use them with my brew python. I installed mapnik with brew install mapnik (mapnik-2.1.0) and it compiled correctly. But, if I open python and enter import mapnik, the following error comes and python exits:
>>> import mapnik
Fatal Python error: PyThreadState_Get: no current thread
Abort trap: 6
Mac os x also shows an error window, with the following content:
Process: Python [60666]
Path: /usr/local/Cellar/python/2.7.3/Frameworks/Python.framework/Versions/2.7/Resources/Python.app/Contents/MacOS/Python
Identifier: Python
Version: 2.7.3 (2.7.3)
Code Type: X86-64 (Native)
Parent Process: bash [60454]
User ID: 501
Date/Time: 2013-03-28 10:21:08.535 +0100
OS Version: Mac OS X 10.8.3 (12D78)
Report Version: 10
Interval Since Last Report: 128837 sec
Crashes Since Last Report: 5
Per-App Crashes Since Last Report: 4
Anonymous UUID: 567121E6-7BAC-335F-E3B0-DD24D1F9E6BA
Crashed Thread: 0 Dispatch queue: com.apple.main-thread
Exception Type: EXC_CRASH (SIGABRT)
Exception Codes: 0x0000000000000000, 0x0000000000000000
Application Specific Information:
abort() called
Thread 0 Crashed:: Dispatch queue: com.apple.main-thread
0 libsystem_kernel.dylib 0x00007fff94500d46 __kill + 10
1 libsystem_c.dylib 0x00007fff92afddf0 abort + 177
2 org.python.python 0x0000000105a77eaa Py_FatalError + 49
3 org.python.python 0x0000000105a76370 PyThreadState_Get + 28
4 org.python.python 0x0000000105a71f16 Py_InitModule4_64 + 58
5 libboost_python-mt.dylib 0x0000000104153288 boost::python::detail::init_module(char const*, void (*)()) + 40
6 org.python.python 0x00000001029fa716 _PyImport_Lo