currently i am having much difficulty thinking of a good method of removing the gradient from a image i received.

The image is a picture taken by a microscope camera that has a light glare in the middle. The image has a pattern that goes throughout the image. However i am supposed to remove the light glare on the image created by the camera light.

Unfortunately due to the nature of the camera it is not possible to take a picture on black background with the light to find the gradient distribution. Nor do i have a comparison image that is without the gradient. (note- the location of the light glare will always be consistant when the picture is taken)

In easier terms its like having a photo with a flash in it but i want to get rid of the flash. The only problem is i have no way to obtaining the image without flash to compare to or even obtaining a black image with just the flash on it.

My current thought is conduct edge detection and obtain samples in specific locations away from the edges (due to color difference) and use that to gauge the distribution of gradient since those areas are supposed to have relatively identical colors. However i was wondering if there was a easier and better way to do this.

If needed i will post a example of the image later.

At the moment i have a preferrence of solving this in c++ using opencv if that makes it easier.

thanks in advance for any possible ideas for this problem. If there is another link, tutorial, or post that may solve my problem i would greatly appreciate the post.

enter image description here

as you can tell there is a light thats being shinned on the img as you can tell from the white spot. and the top is lighter than the bottome due to the light the color inside the oval is actually different when the picture is taken in color. However the color between the box and the oval should be consista

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