Architectual design patterns

I am looking for some architectual design patterns for enterprise application development. I am aware of the all of the GoF patterns, and MVC, and such things, but I am looking for patterns that emerge at a larger scope. In particular I have a somewhat larger enterprise desktop and website application, they share certain functionality, and some is unique, and I am looking for best practices on how to structure the entire solution, how to expose business logic domains to others via factories, or such, and generally things of this nature that deal with the entire application as a whole.