I would be interested to learn about large scale development in Python and especially in how do you maintain a large code base?
When you make incompatibility changes to the signature of a method, how do you find all the places where that method is being called. In C++/Java the compiler will find it for you, how do you do it in Python?
When you make changes deep inside the code, how do you find out what operations an instance provides, since you don't have a static type to lookup?
How do you handle/prevent typing errors (typos)?
Are UnitTest's used as a substitute for static type checking?
As you can guess I almost only worked with statically typed languages (C++/Java), but I would like to try my hands on Python for larger programs. But I had a very bad experience, a long time ago, with the clipper (dBase) language, which was also dynamically typed.