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None of the above examples (from Derek Ledbetter, David Sorkovsky, and Joe D) to count arguments with macros worked for me using Microsoft VCC 10. The __VA_ARGS__ argument is always considered as a single argument (token-izing it with ## or not), so the argument shifting in which those examples rely doesn't work.
So, short answer, as stated by many others above: no, you can't overload macros or use optional arguments on them.