Is there a downside to using ".filter().filter().filter()..." in Django?

Are the following two calls resolved to the equivalent SQL query in Django?

Chaining multiple calls

Model.objects \
.filter(arg1=foo) \
.filter(arg2=bar) \
...

Wrapping all the args together:

Model.objects \
.filter(arg1=foo, arg2=bar)

I'd like code to be readable (there are MANY more filter calls than I've shown), but only if there's no sacrifice to performance.