Modify bound variables of a closure in Python

Is there any way to modify the bound value of one of the variables inside a closure? Look at the example to understand it better.

def foo():
    var_a = 2
    var_b = 3

    def _closure(x):
        return var_a + var_b + x

    return _closure


localClosure = foo()

# Local closure is now "return 2 + 3 + x"
a = localClosure(1) # 2 + 3 + 1 == 6

# DO SOME MAGIC HERE TO TURN "var_a" of the closure into 0
# ...but what magic? Is this even possible?

# Local closure is now "return 0 + 3 + x"
b = localClosure(1) # 0 + 3 +1 == 4