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Often enough, I've found the need to process a list by pairs. I was wondering which would be the pythonic and efficient way to do it, and found this on Google: pairs = zip(t[::2], t[1::2]) I thought that was pythonic enough, but after a recent discussion involving idioms versus efficiency , I decided to do some tests: import time from itertools import islice, izip def pairs_1(t): return zip(t[::2], t[1::2]) def pairs_2(t): return izip(t[::2], t[1::2]) def pairs_3(t): return izip(islice(t,None,None,2), islice(t,1,None,2)) A = range(10000) B = xrange(len(A)) def pairs_4(t): # ignore value of t! t = B return izip(islice(t,None,None,2), islice(t,1,None,2)) for f in pairs_1, pairs_2, pairs_3, pairs_4: # time the pairing s = time.time() for i in range(1000): p = f(A) t1 = time.time() - s # time using the pairs s = time.time() for i in range(1000): p = f(A) for a, b in p: pass t2 = time.time() - s print t1, t2, t2-t1 These were the results on my computer: 1.48668909073 2.63187503815 1.14518594742 0.105381965637 1.35109519958 1.24571323395 0.00257992744446 1.46182489395 1.45924496651 0.00251388549805 1.70076990128 1.69825601578 If I'm interpreting them correctly, that should mean that the implementation of lists, list indexing, and list slicing in Python is very efficient. It's a result both comforting and unexpected. Is there another, "better" way of traversing a list in pairs? Note that if the list has an odd number of elements then the last one will not be in any of the pairs. Which would be the right way to ensure that all elements are included? I added these two suggestions from the answers to

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