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I think it depends on what matters to you. Give BlogEngine.net a try and give Wordpress a try. This isn't our blog it's yours. I usually find using it for about 1-3 weeks messing with features and just what feels right for me works the best.
I run a single user blog and a .Net developer. After checking out BlogEngine.Net and dasblog tonight I will be moving from WordPress to BlogEngine.Net. (Nothing really bad to say about Wordpress I just want to be running on a .Net platform)