ClickOnce setup.exe fails, but the .application file works fine when using a Windows share for deployment

I am getting the error of System.Deployment.Application.DeploymentDownloadException when I try to run setup.exe for my ClickOnce application. If run it over the network from its original location it works fine, but if I copy setup.exe from the path on the server I get the error

Can not download application. The Application is missing required files.

I need the setup as it installs some prerequisites (.NET 4) that the end user may not have.

Clicking the details button from the error window gives the following information:

PLATFORM VERSION INFO
    Windows             : 6.1.7601.65536 (Win32NT)
    Common Language Runtime     : 4.0.30319.237
    System.Deployment.dll       : 4.0.30319.1 (RTMRel.030319-0100)
    clr.dll             : 4.0.30319.237 (RTMGDR.030319-2300)
    dfdll.dll           : 4.0.30319.1 (RTMRel.030319-0100)
    dfshim.dll          : 4.0.31106.0 (Main.031106-0000)

SOURCES
    Deployment url          : file:///C:/Users/srchamberlain/Downloads/ContractFlowTool.application

ERROR SUMMARY
    Below is a summary of the errors, details of these errors are listed later in the log.
    * Activation of C:\Users\srchamberlain\Downloads\ContractFlowTool.application resulted in exception. Following failure messages were detected:
        + Downloading file:///C:/Users/srchamberlain/Downloads/ContractFlowTool.application did not succeed.
        + Could not find file 'C:\Users\srchamberlain\Downloads\ContractFlowTool.application'.
        + Could not find file 'C:\Users\srchamberlain\Downloads\ContractFlowTool.application'.
        + Could not find file 'C:\Users\srchamberlain\Downloads\ContractFlowTool.application'.

COMPONENT STORE TRANSACTION FAILURE SUMMARY
    No transaction error was detected.

WARNINGS
    There were no warnings during this operation.

OPERATION PROGRESS STATUS