Why does the order of loops in a matrix multiply algorithm affect performance?

I am given two functions for finding the product of two matrices:

 void MultiplyMatrices_1(int **a, int **b, int **c, int n){
      for (int i = 0; i < n; i++)
          for (int j = 0; j < n; j++)
              for (int k = 0; k < n; k++)
                  c[i][j] = c[i][j] + a[i][k]*b[k][j];
  }

 void MultiplyMatrices_2(int **a, int **b, int **c, int n){
      for (int i = 0; i < n; i++)
          for (int k = 0; k < n; k++)
              for (int j = 0; j < n; j++)
                  c[i][j] = c[i][j] + a[i][k]*b[k][j];
 }

I ran and profiled two executables using gprof, each with identical code except for this function. The second of these is significantly (about 5 times) faster for matrices of size 2048 x 2048. Any ideas as to why?