Is there a difference between HDF5 files and files created by PyTables?

PyTables has two functions .isHDFfile() and .isPyTablesFile() suggesting that there is a difference between the two formats.

I've done some looking around on Google and have gathered that PyTables is built on top of HDF, but I wasn't able to find much beyond that.

I am specifically interested in interoperability, speed and overhead.

Thanks.

python numpy hdf5 pytables
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