Is this possible, with CSS ?

Apply this rule if .div1 doesn't exist:

.div2{
  property: value;  
}

like

<div class="div1">
...
</div>

<div class="div2">
 <!-- it exists, so do nothing -->
</div>

and

<div class="div2">
 <!-- it doesn't exist, apply the css -->
</div>
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