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Extension Method Performance

Will I face performance issues when I´m using extension methods too heavy in any way?

Just an example:

Lets say I´ve 100 extension methods on the type string and a business object that has 50 string properties. Now I create a collection of this business object, maybe 500 items?

Do these extension methods on string have any impact to RAM, CPU, ...?!

I really like extension methods but I´d like to know if there is a limitation concerning its usage.

c# .net performance extension-methods
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